Tag: M.W=100-200

Related Products of 317-20-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 317-20-4, name is 7-Fluoroisatin belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.

General procedure: The mixture of isatin (1 mmol), 3-amino-1-phenyl-1H-pyrazol-5(4H)-one (1 mmol), 1,2-diarylethan-1-one, 2,3-dihydroinden-1-one (1 mmol) or 3,4-dihydronaphthalen-1(2H)-one (1 mmol), H2O (6 mL), HOAc (2 mL) was put in a reaction flask under 90 C about 5-7 h (monitored by TLC). After completion, the reaction mixture was cooled to room temperature and the products would be isolated out at same time. Then, compound 4 was recrystallized from DMF, however, the pure products of 6 and 8 were filtered from water, dried, without further recrystallization.

The synthetic route of 7-Fluoroisatin has been constantly updated, and we look forward to future research findings.

Reference of 20870-79-5, A common heterocyclic compound, 20870-79-5, name is 5-Nitroindolin-2-one, molecular formula is C8H6N2O3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

5-Amino-2-oxindole 5-Nitro-2-oxindole (6.3 g) was hydrogenated in methanol over 10% palladium on carbon to give 3.0 g (60% yield) of the title compound as a white solid.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 114041-16-6, name is 5,6-Dimethoxyisoindoline, A new synthetic method of this compound is introduced below., Formula: C10H13NO2

Step 8) 2-c oropyrimidine derivative 11 (5.84 g, 42.0 mmol), DIEA (8 mL, 46 mmol) and isoindoline (7.52 mg, 42.0 mmol) were dissolved in Acetonitrile (100 mL) and the mixture was heated to 80C and stirred for 1 hour. The solvent was removed by concentration and water was added. The solid was collected with filtration, washed with water and dried under air. The crude 12 was used in the next step directly without further purification.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference of 32692-19-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 32692-19-6, name is 5-Nitroindoline, This compound has unique chemical properties. The synthetic route is as follows.

A. Synthesis of tert-butyl 5-nitro-2,3-dihvdro-1H-indole-1-carboxylate. To a stirred solution of 5-nitroindoline (0.50 g, 3.0 mmol) and di-tert-butyl dicarbonate (0.97 g, 4.4 mmol) in anhydrous tetrahydrofuran (10 mL) was added 4- dimethylaminopyridine (0.054 g, 0.44 mmol) at ambient temperature. The reaction mixture was stirred at 60 0C for three hours. Water was added slowly to quench the reaction. The reaction mixture was poured into saturated sodium bicarbonate solution (100 mL). The mixture was extracted with ethyl acetate (3 x 30 mL). The combined organic layers was dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated in vacuo to give tert-butyl 5-nitro-2,3-dihydro-1H-indole-1 -carboxylate (0.77 g, 98%) as a brown solid: 1H NMR (300 MHz, CDCI3) delta 8.07 (dd, J = 9.0, 2.4 Hz, 1 H), 7.97 (d, J = 1.2 Hz, 1 H), 7.94-7.50 (br, 1 H), 4.06 (t, J = 8.8 Hz, 2H), 3.14 (t, J = 8.8 Hz, 2H), 1.55 (s, 9H).

The chemical industry reduces the impact on the environment during synthesis 5-Nitroindoline. I believe this compound will play a more active role in future production and life.

Related Products of 59-48-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 59-48-3, name is Indolin-2-one, This compound has unique chemical properties. The synthetic route is as follows.

Preparation of 5-nitro-oxindole To a solution of oxindole (26 g) in 100 mL of concentrated sulfuric acid at -15 C. was added fuming nitric acid (8.4 mL) dropwise. Careful attention was paid to maintain the reaction temperature at -15 C. After the addition was complete, the reaction was stirred for 30 minutes and then poured into ice water. A yellow precipitate was formed which was isolated by filtration to provide 34 grams (98%) of 5-nitro oxindole.

The chemical industry reduces the impact on the environment during synthesis Indolin-2-one. I believe this compound will play a more active role in future production and life.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 100510-65-4, name is 6-Amino-3,3-dimethylindolin-2-one, A new synthetic method of this compound is introduced below., Recommanded Product: 6-Amino-3,3-dimethylindolin-2-one

(f) 6-Acetamido-3,3-dimethylindolin-2-one 20.4 g. (0.2 mol) Acetic anhydride are added dropwise, with cooling, to a suspension of 32 g. (0.18 mol) 6-amino-3,3-dimethyl-indolin-2-one in 500 ml. ethyl acetate and then stirred for about 1 hour at ambient temperature. The resultant product is filtered off with suction, well washed with ethyl acetate and dried. Yield: 37.8 g. (96% of theory); m.p. 275-277 C. The following compound is obtained in a manner analogous to that described in (f):

The synthetic route of 100510-65-4 has been constantly updated, and we look forward to future research findings.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 6872-06-6, name is 2-Methylindoline, A new synthetic method of this compound is introduced below., SDS of cas: 6872-06-6

General procedure: 2-Methylindoline (400 mg, 3.0 mmol, 1.0 equiv) was dissolved in dry pyridine (10 mL). Methane sulfonyl chloride (480 mg, 4.2 mmol, 1.4 equiv) was added dropwise and the reaction mixture was stirred overnight at rt. Monitoring by HPLC and LCMS indicated that the reaction was completed. The solvent was evaporated under reduced pressure. A solution of HCl 1N (50 mL) and EtOAc (50 mL) were added. The organic layer was separated and the aqueous phase was extracted twice with EtOAc (2×50 mL). The combined organic phase was dried over Na2SO4 and the solvent was evaporated under reduced pressure to yield the pure product: 634 mg, 100 % yield.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Application of 6341-92-0,Some common heterocyclic compound, 6341-92-0, name is 6-Chloroisatin, molecular formula is C8H4ClNO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

4. 6-Chlorooxindole Reaction of 36.2 g. of 6-chloroisatin with hydrazine hydrate followed by sodium ethoxide in ethanol, substantially according to B above, afforded 14.2 g. of 6-chlorooxindole, m.p. 196-198 C. In an analogous manner 4- and 6-fluoro- and bromooxindoles are prepared, as well as 7-fluorooxindole, 7-bromooxindole, 7-methyloxindole, 4,6-difluorooxindole, 4,7-dichlorooxindole, 5,7-difluorooxindole, 5-n-butyl-7-fluorooxindole, 7-cyclohexyloxindole and 7-cyclopropyloxindole.

The synthetic route of 6341-92-0 has been constantly updated, and we look forward to future research findings.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: indolines-derivatives, 56341-37-8, Name is 6-Chlorooxindole, molecular formula is C8H6ClNO, belongs to indolines-derivatives compound. In a document, author is Youssef, M. Adel, introduce the new discover.

A set of dispiro[indoline-3,2 ‘-pyrrolidine-3 ‘,3 ”-pyrrolidines]8a-lwas regioselectively synthesized utilizing multi-component azomethine cycloaddition reaction of 3-(arylmethylidene)pyrrolidine-2,5-diones5a-e, isatins6a-cand sarcosine7. Single crystal X-ray studies of8cadd conclusive support for the structure. Compounds8eand8greveal cholinesterase inhibitory properties with promising efficacy against both AChE and BChE and were found to be more selective towards AChE than BChE as indicted by the selectivity index like Donepezil (a clinically used cholinesterase inhibitory drug). Molecular modeling studies assist in understanding the bio-observations and identifying the responsible parameters behind biological properties.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 56341-37-8. Category: indolines-derivatives.

Reference:
Indoline – Wikipedia,
,Indoline | C8H9N – PubChem

550-44-7, Name is 2-Methylisoindoline-1,3-dione, molecular formula is C9H7NO2, HPLC of Formula: https://www.ambeed.com/products/550-44-7.html, belongs to indolines-derivatives compound, is a common compound. In a patnet, author is Bao, Bingwei, once mentioned the new application about 550-44-7.

Photochromic materials have drawn growing interesting due to their capability of interconversion under the action of external optical stimulation, allowing diverse potential applications. Herein, we proposed a novel method of preparing photochromic cotton fabric coated by combined l-(2-hydroxyethyl)-3,3-dimethyl-6-nitrospiro [l(2H)-benzopyran-2,2-indoline] terminated waterborne polyurethane. The synthesized photochromic compounds 1-(2-hydroxyethyl)-3,3-dimethyl-6-nitrospiro[1(2H)-benzopyran-2,2-indoline] (SP-OH), were characterized by FTIR spectra, H-1 NMR and ultraviolet (UV) spectrum. The as-prepared spiropyran-terminated water polyurethane (SP-OH/WPU) was characterized via FTIR spectra, ultraviolet (UV) spectrum, SEM and size analysis. The photochromic cotton fabric was featured via FTIR spectra, ultraviolet (UV) spectrum and SEM. In addition, the photochromic properties, thermal stability of as-prepared cotton fabric was tested. The results showed that the photochromic compounds and SP-OH/WPU have been successfully synthesized and the resultant cotton fabric possesses excellent and durable photochromic properties, including noticeable and quick color alteration under UV radiation and fast recovery when exposed to green light. Furthermore, the excellent thermal stability ensured it undergo harsh service environment, which indicated that it is a good candidate for photochromic textile.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 550-44-7 help many people in the next few years. HPLC of Formula: https://www.ambeed.com/products/550-44-7.html.

Reference:
Indoline – Wikipedia,
,Indoline | C8H9N – PubChem