Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 114041-16-6, name is 5,6-Dimethoxyisoindoline, A new synthetic method of this compound is introduced below., Formula: C10H13NO2
Step 8) 2-c oropyrimidine derivative 11 (5.84 g, 42.0 mmol), DIEA (8 mL, 46 mmol) and isoindoline (7.52 mg, 42.0 mmol) were dissolved in Acetonitrile (100 mL) and the mixture was heated to 80C and stirred for 1 hour. The solvent was removed by concentration and water was added. The solid was collected with filtration, washed with water and dried under air. The crude 12 was used in the next step directly without further purification.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.