Application of 3891-07-4, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3891-07-4, name is 2-(2-Hydroxyethyl)isoindoline-1,3-dione, This compound has unique chemical properties. The synthetic route is as follows.
2) A light yellow solid powder (compound represented by Structural Formula II) 74g was added to a 1000 ml round bottom flask.N-hydroxyethyl phthalimide 37.4g,Potassium carbonate 13g,N,N-dimethylformamide 1.3g,Methyl ethyl ketone 300g, stirring,Heating at 80 C reflux, the reaction for 8 h;After the reaction was completed, it was cooled to 40 C, 200 g of water was added, stirred for 1 h, filtered, and the filter cake was vacuum dried at 50 C for 12 h.87.7 g of a white solid powder (compound of formula III) was obtained.The crude yield was 95% and the purity was 97.932%.
The chemical industry reduces the impact on the environment during synthesis 2-(2-Hydroxyethyl)isoindoline-1,3-dione. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Nanjing Yuanshu Pharmaceutical Technology Co., Ltd.; Jin Feng; Zhou Taiyong; Wang Kai; Xiao Liang; Chun Qingyan; (11 pag.)CN109721587; (2019); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem