Share a compound : 1074-82-4

Reference of 1074-82-4, These common heterocyclic compound, 1074-82-4, name is Potassium 1,3-dioxoisoindolin-2-ide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Reference of 1074-82-4, These common heterocyclic compound, 1074-82-4, name is Potassium 1,3-dioxoisoindolin-2-ide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Potassium phthalimide (49 gm) was added to a solution of (Z)- 1 -phenyl- 1- diethylamino carbonyl-2-chloromethyl cyclopropane obtained in step-(c) at 20-30C. The reaction mixture was heated to 80-85C, stirred for 2-3 hrs at the same temperature and then cooled to 20-30C. The resulting reaction mixture containing (Z)- 1 -phenyl- 1- diethylaminocarbonyl-2-phthalimidomethyl cyclopropane was utilized in the next step without isolating the compound from the reaction mixture.

Statistics shows that Potassium 1,3-dioxoisoindolin-2-ide is playing an increasingly important role. we look forward to future research findings about 1074-82-4.

Reference:
Patent; MSN LABORATORIES LIMITED; THIRUMALAI RAJAN, Srinivasan; ESWARAIAH, Sajja; SATYANARAYANA, Revu; WO2012/46247; (2012); A2;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem