Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 19727-83-4, name is 6-Nitroindoline, This compound has unique chemical properties. The synthetic route is as follows., category: indolines-derivatives
4.92 g (0.03 mol) of 6-nitro-2,3-dihydro-1H-indole (16) was dispersed in 50 ml of dimethylformamide under nitrogen atmosphere and stirred at room temperature for about 10 minutes. Then, 5.3 g mol) and 6.1 ml (0.036 mol) of diisopropylethylamine (DIPEA) were successively added to the reaction mixture. The reaction solution was gradually heated and stirred at 70 C for 4 hours to complete the reaction. After cooling the reaction mixture to room temperature, 100 ml of distilled water and 200 ml of ethyl acetate were added and the mixture was stirred for 30 minutes. The organic layer was separated and washed with H 2 O. The recovered organic layer was dried over anhydrous magnesium sulfate and the solvent was distilled off under reduced pressure 7.41 g (97.2%) of 6-nitro-2,3-dihydro-1- (1-phenylmethyl) -1H-indole (73) as a yellowish liquid was obtained.
According to the analysis of related databases, 19727-83-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Korea Research Institute of Chemical Technology; Shin Seung-rim; Jeon Geun; Shin Jong-il; Park Yeong-il; Ahn Gyeong-ryong; (48 pag.)KR101842495; (2018); B1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem