In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1074-82-4, name is Potassium 1,3-dioxoisoindolin-2-ide belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below. Safety of Potassium 1,3-dioxoisoindolin-2-ide
Compound 4 (1.86g, 10mmol) and 1,6-b hexyl bromide (12.2g, 50mmol) in dry DMF (10 ml) and heated to 100 C, thermal insulation 12h. Then the excess is removed by reduced pressure distillation 1,6-b hexyl bromide. The silica gel column for separation and purification of the crude product (showering liquid is ethyl acetate/petroleum ether, volume ratio of 1:40), be 2.5g compound 5 (colorless powder), yield 81%.
The synthetic route of 1074-82-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jiangsu Hecheng Advanced Materials Co., Ltd; Kongxiang, Fei; Huang, Da; Wanggui, Xia; Liu, Canhui; Tan, Yudong; (22 pag.)CN105461628; (2016); A;,
Indoline – Wikipedia,
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