Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3891-07-4, name is 2-(2-Hydroxyethyl)isoindoline-1,3-dione, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C10H9NO3
To a solution of 2-(2-hydroxyethyl)isoindoline-1,3-dione (1.68 mmol) in methylene chloride (10 mL) was added ADDP (1.68 mmol), triphenylphosphine (1.68 mmol) and phenol (3.18 mmol) and stirred at room temperature. After stirring overnight, the reaction mixture was diluted with methylene chloride (30 mL) and washed with 1 M NaOH aqueous solution (50 mL), and brine (50 mL). The organic layer was dried over anhydrous MgSO4 and concentrated in vacuo. The crude product was purified by silica gel flash column chromatography (4:1 hexanes/ethyl acetate) and recrystallized from a mixture of hexanes and ethyl acetate to give A1.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 3891-07-4.
Reference:
Patent; Brodin, Priscille; Christophe, Thierry; No, Zaesung; Kim, Jaeseung; Genovesio, Auguste; Fenistein, Denis Philippe Cedric; Jeon, Heekyoung; Ewann, Fanny Anne; Kang, Sunhee; Lee, Saeyeon; Seo, Min Jung; Park, Eunjung; Contreras Dominguez, Monica; Nam, Ji Youn; Kim, Eun Hye; US2011/178077; (2011); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem