The important role of 1498-88-0

1498-88-0, name is 1′,3′,3′-Trimethyl-6-nitrospiro[chromene-2,2′-indoline], belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of 1′,3′,3′-Trimethyl-6-nitrospiro[chromene-2,2′-indoline]

1498-88-0, name is 1′,3′,3′-Trimethyl-6-nitrospiro[chromene-2,2′-indoline], belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of 1′,3′,3′-Trimethyl-6-nitrospiro[chromene-2,2′-indoline]

General procedure: Trifluoroacetic acid (13.9 mmol) was added to a solution of the corresponding hybrid compound 1a-c (13.9 mmol) in toluene (10 ml). For neutralization of acid the equimolar quantity of triethylamine was added. Spectrophotometric measurements for solutions were carried out on an Agilent Cary 60 Bio spectrophotometer in a KU-1 quartz cell with optical path length of 2 mm. The isomerization was investigated at room temperature for 0.2 mm solutions of 1a-c.

The synthetic route of 1498-88-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Tuktarov, Airat R.; Khuzin, Artur A.; Dzhemilev, Usein M.; Mendeleev Communications; vol. 29; 2; (2019); p. 229 – 231;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem